Route 22 runs from Meijer on Carpenter Road, east on Washtenaw to Glencoe Crossing, and then west and north to North Campus.

The northbound route is a continuation of AATA Route 5.

Route changes January 2010

Northbound trips will continue the long-term detour on Washtenaw east of Carpenter Road before heading west to the Arborland area to provide for safe transfers with other buses. Timepoint adjustments will be made at several places along Route 22. In addition, Route 22 will now serve the Glazier Way and Earhart Road neighborhoods on Saturdays. Direct service to the VA Medical Center will no longer be available on Saturdays.