- 111 South Main
- 301 South Main Street
- 600 South Main Street
- 618 South Main
- 637 S. Main Street
- A3 Integration
- Annabelle Jewelry
- Ann Arbor School for the Performing Arts
- Ann Arbor Shoe Repair
- Arbor Dog Daycare
- Ardesta
- Ashley Mews
- Back Alley Gourmet
- Barclay Gallery
- BD's Mongolian Barbeque
- Bennett Optometry
- Blue House Ann Arbor
- Brazamerica
- Brickyard
- Busch's
- Busy Hands
- By The Pound
- Celtic Room
- Citizens Bank (former)
- Conor O'Neill's
- Copernicus European Delicatessen
- Crazy Wisdom
- Cyndi Clark
- Elmo's Hideaway
- Elmo's T-Shirts
- Footprints
- Glazier Building
- Great Harvest Bread Company
- Happy's Pizza
- Hollway Field
- Integrative Pediatrics
- Japanese Auto Professional
- Jazzy Veggie
- Jolly Pumpkin Artisan Ales
- Kai Garden
- Key Bank
- Keystone Media
- La Belle Maison
- La Seine
- Lena
- Main Street BIZ
- Mayer Schairer Building
- Melange Bistro
- Michigan Stadium
- Middle Kingdom
- MSBIZI
- Occasionally Gift Shop
- Of Global Interest LLC
- Overture Audio
- Palio
- Parthenon
- Peaceable Kingdom
- People's Choice Alternative Medicine
- Phoenix Center
- Pratt Block
- Quack!Media
- Quality Bar
- Real Seafood
- RUB
- Rush Street
- San Fu
- Selo/Shevel Gallery
- Seyfried Jewelers
- Shahin Clothing
- Shalimar
- S Main St (Ann Arbor)
- Stadium Commons
- Ten Thousand Villages
- The Ark
- The Black Pearl
- The Chop House
- The Himalayan Bazaar
- The Puck Drops Here
- The Residences at 615 South Main
- The UPS Store
- Tom Thompson Flowers
- University Living
- Van's Market
- Vellum
- Vinology
- Westphal Associates
- Workantile
- WSG Gallery