The Federal Bureau of Investigation has been involved in Oakland affairs from time to time. In the 1960s and 1970s as part of J Edgar Hoover's COINTELPRO program, the FBI infiltrated anti-war, socialist, and revolutionary groups like the Black Panthers with paid informants.

As of 2015, city council has approved a "secured room for as many as 10 FBI agents and several officers at the downtown Oakland Police Administration Building."