The Run Drugs Out of Town 5K Run/Walk has been held annually since 2005. It takes place on the last Saturday in April at the River Valley High School football stadium in Yuba City. It is a family event, a competitive five-kilometer run or walk for all ages and also a quarter-mile kids' run. No alcohol, tobacco, or drugs allowed. The event is sponsored by the Substance Abuse Steering Coalition.

Registration starts at 7:00 a.m., and the run/walk starts at 9:00 a.m. The fee is $15 for adults and $10 for children in advance. Two or more children are $7.50 each. Price increases to $15 for adults on the day of the event.